genotype-to-phenotype prediction
LSTM Autoencoder-based Deep Neural Networks for Barley Genotype-to-Phenotype Prediction
Wang, Guanjin, Xuan, Junyu, Wang, Penghao, Li, Chengdao, Lu, Jie
Artificial Intelligence (AI) has emerged as a key driver of precision agriculture, facilitating enhanced crop productivity, optimized resource use, farm sustainability, and informed decision-making. Also, the expansion of genome sequencing technology has greatly increased crop genomic resources, deepening our understanding of genetic variation and enhancing desirable crop traits to optimize performance in various environments. There is increasing interest in using machine learning (ML) and deep learning (DL) algorithms for genotype-to-phenotype prediction due to their excellence in capturing complex interactions within large, high-dimensional datasets. In this work, we propose a new LSTM autoencoder-based model for barley genotype-to-phenotype prediction, specifically for flowering time and grain yield estimation, which could potentially help optimize yields and management practices. Our model outperformed the other baseline methods, demonstrating its potential in handling complex high-dimensional agricultural datasets and enhancing crop phenotype prediction performance.
- Oceania > Australia > Western Australia > Perth (0.04)
- Oceania > Australia > New South Wales > Sydney (0.04)
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- Health & Medicine (1.00)
- Food & Agriculture > Agriculture (1.00)
RandomSCM: interpretable ensembles of sparse classifiers tailored for omics data
Godon, Thibaud, Plante, Pier-Luc, Bauvin, Baptiste, Francovic-Fontaine, Elina, Drouin, Alexandre, Corbeil, Jacques
Background: Understanding the relationship between the Omics and the phenotype is a central problem in precision medicine. The high dimensionality of metabolomics data challenges learning algorithms in terms of scalability and generalization. Most learning algorithms do not produce interpretable models -- Method: We propose an ensemble learning algorithm based on conjunctions or disjunctions of decision rules. -- Results : Applications on metabolomics data shows that it produces models that achieves high predictive performances. The interpretability of the models makes them useful for biomarker discovery and patterns discovery in high dimensional data.